The results of the error analysis indicated that the modified Apelblat equation was able to give more accurate and reliable predictions of solubility with the relative average deviation (RAD) and root-mean-square deviation (RMSD) values being observed in the range of 0.21-0.67% and 0.01-0.13%, respectively. The results showed that the solubility of acetylpyrazine generally rises with the increase of solvent polarity at the same temperature. Solubility B Liang Zhu email@example.com 1 Tianjin Key Laboratory of Marine Resources and Chemistry, College of Material Science and Chemical Engineering, Tianjin University of Science and Technology, Tianjin 300457, Quality confirmed by NMR & HPLC. Raspberry ketone shows cardioprotective action against isoproterenol-induced myocardial infarction in rats, and the effects may be due to its PPAR-α agonistic activity. The raspberry precursor 4-(4-hydroxyphenyl)-but-3-ene-2-one which afterwards undergoes a catalytic hydrogenation to produce raspberry ketone was synthesized by aldol condensation of acetone and 4-hydroxybenzaldehyde over rare earth oxides as basic catalysts and supported rare earth oxides as acid-base bifunctional catalysts. It was found that the solubility of sorbic acid in the three binary solvent systems increased with increasing temperature as well as increasing initial mole fraction of organic solvent in these systems. Update 9/14/19. The solubilities of metoprolol succinate (a cardioselective β1 adrenergic receptor) in methanol, ethanol, n-propanol, isopropanol, n-butanol, ethyl acetate, and acetone were measured at temperatures ranging from (278.2 to 318.2) K using a solid⁻liquid equilibrium method. The objective of this work was to measure and correlate the solubility of 4-hydroxy-2,5-dimethyl-3(2H)-furanone (DMHF) in six pure solvents, including methanol, ethanol, n-propyl alcohol, n-butyl alcohol, n-hexane and distilled water, over the temperature range from 283.15 K to 313.15 K under atmospheric pressure of 0.10 MPa. The solubility of metoprolol succinate increases with increasing temperature. The solubility data of sorbic acid in binary systems of (ethanol + water), (1-propanol + water) and (2-propanol + water) were measured from 283.15 to 323.15 K using the static equilibrium method under atmospheric pressure. Furthermore, the dissolution thermodynamic properties of Gibbs energy change (ΔsolGo), molar enthalpy change (ΔsolHo) and molar entropy change (ΔsolSo) were calculated from the experimental solubility data, using the van’t Hoff equation. PubMed:Raspberry ketone protects rats fed high-fat diets against nonalcoholic steatohepatitis. The positive values of the ΔdissH°, ΔdissS° and ΔdissG° revealed the dissolution process of DMHF in the selected solvents was endothermic and enthalpy-driven. It increases your metabolism and burns fat fast. The modified Apelblat equation was therefore used to estimate the changes of dissolution enthalpy (ΔdissH°), dissolution entropy (ΔdissS°) and molar Gibbs free energy (ΔG°diss) of DMHF in the solvents investigated. The solubility of 1,3-diphenylguanidine in the selected solvents increased with the increase in, The solubility and dissolution thermodynamic properties of raspberry ketone in a set of binary solvent mixtures (ethanol + water) with different compositions were experimentally determined by static gravimetrical method in the temperature range of 283.15–313.15 K at 0.10 MPa. The quality/contaminations of the starting material have a strong influence on the catalytic performance. The deliquescent rules can be acquired by using modified Apelblat equation, van't Hoff equation, λh equation, Wilson model, Non-Random Two Liquid (NRTL) model, Universal Quasi–Chemical (UNIQUAC) Model and modified Jouyban-Acree model. According to the ever popular Dr. Oz show on Fox 5, two of the newest ways to shed pounds and maintain a healthy weight are entirely all natural -- green coffee bean extract and raspberry ketone. Raspberry ketone is sometimes used in perfumery, in cosmetics, and as a food additive to impart a fruity odor. The solubility of Raspberry Ketone was measured from (293.15 to 333.15) K. The solubility data of Raspberry Ketone was well correlated by seven models. formula . The measured solubility data of pranlukast hemihydrate were correlated with the modified Apelblat and Van't Hoff models. The solubility of DMHF in all the selected solvents was found to increase with rising temperature, and methanol has much more dissolving capacity for the DMHF solute. Recommendation for raspberry ketone acetate usage levels up to: 6.0000 % in the fragrance concentrate. In contrast to the complex mixture of other aromas that alter rapidly if the composition of their multiple compounds is not maintained raspberry ketone is the single dominant volatile that defines raspberry aroma . The modified Apelblat equation shows the best agreement in general. Copyright © 2015. Raspberry Ketone. Solubility(ies) Solubility (water) Insoluble Partition coefficient (n-octanol/water) Not available. The solubility data were correlated with some thermodynamic models, including the modified Apelblat model, λh model, CNIBS/R-K model, and NRTL model. The maximum mole fraction solubility of pranlukast hemihydrate in 1-butanol was observed to be 26.39 × 10− 5 at 323.15 K, followed by that in 1-propanol (9.63 × 10− 5 at 323.15 K), ethanol (6.18 × 10− 5 at 323.15 K), 2-propanol (5.71 × 10− 5 at 323.15 K), and methanol (3.96 × 10− 5 at 323.15 K). The experimental solubility of DMHF in pure solvents was well correlated with the modified Apelblat equation, van't Hoff equation and λh equation. In this study, the solubility of Raspberry Ketone in nine mono-solvents, including ethanol, 1-propanol, 2-propanol, 1-butanol, 2-butanol, acetic acid, methyl acetate, ethyl acetate, acetone, and binary mixtures of ethanol + acetone (the mass fraction of ethanol varied from 0.1 to 0.9, in intervals of 0.1) was measured at (293.15 to 333.15) K in atmospheric pressure by shake-flask method. Raspberry ketone in food supplements – High intake, few toxicity data – A cause for safety concern? The solubility of complex triterpenes Lup-20(29)-ene-3β,28-diol (betulin) and (8R,9S,13S,14S)-3-hydroxy-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydrocyclopenta[a]phenanthren-17-one (estrone) in numerous common solvents were determined by combined thermal gravimetry and digital thermal analysis (TGA/DTA). The target of this work is to measure and correlate the solubility of Raspberry Ketone, and obtain the thermodynamic parameters simultaneously. The measured solubility data of pranlukast hemihydrate correlated well with the modified Apelblat equation. The acquired solubility of 1,3-diphenylguanidine were correlated with the Apelblat equation, equation, Wilson model and NRTL model, and the the corresponding model parameters were obtained. The modified Apelblat equation, Wilson model, and non-random two-liquid (NRTL) model were employed to correlate the solubilities of metoprolol succinate in different solvents. Raspberry ketone glucoside Methods for cleaning up Wear protective clothing as described in Section 8 of this safety data sheet. At a fixed temperature, the solubility decreases in the order methanol > ethanol > n-butanol > n-propanol > isopropanol > acetone > ethyl acetate. Raspberry ketone (10 µM) significantly blocks C/EBPα, PPARγ, and aP2 expression and increases the expression of ATGL and HSL, and CPT1B.. MCE has not independently confirmed the accuracy of these methods. The experimental data correlated well with the modified Apelblat equation, the simplified polynomial empirical equation, NRTL model and UNIQUAC model. The positive values of the ΔdissH°, ΔdissS° and ΔdissG° revealed the dissolution process of DMHF in the selected solvents was endothermic and enthalpy-driven. The former two models could reach better fitting results with the solubility data, while the 3D model can be comprehensively used to estimate the solubility data in all the ratios of ethanol and water in binary solvent mixtures at random temperature. Furthermore, the changes of dissolution enthalpies (ΔdissH°), dissolution entropies (ΔdissS°) and dissolution Gibbs energies (ΔdissG°) of raspberry ketone in the solvents studied were estimated by the van’t Hoff equation. The results of the error analysis indicated that the modified Apelblat equation was able to give more accurate and reliable predictions of solubility with the relative average deviation (RAD) and root-mean-square deviation (RMSD) values being observed in the range of 0.21-0.67% and 0.01-0.13%, respectively. Solubility and Solution Thermodynamic Properties of 4-(4-Hydroxyphenyl)-2-butanone (Raspberry Ketone) in Different Pure Solvents October 2017 Journal of Solution Chemistry 46(11) L-arabinose and D-galactose could be released during the hydrolysis process of Arabic gum. The results show that the solubility of OTBNBr monotonously increases with increasing temperature and increasing mole fraction of acetone. Consequently, the solubility results of this study would be useful in purification, crystallization, recrystallization and a new synthetic route design of Raspberry Ketone. The solubility of 4-(4-hydroxyphenyl)-2-butanone (raspberry ketone) in six pure solvents was experimentally determined at temperatures ranging from 283.15 to 313.15 K under the pressure 0.10 MPa by employing a gravimetrical method. The experimental data show highly conformance with the calculated data which obtain from all the selected models. The compound can be produced by organic synthesis. In this study, the solubility of pranlukast hemihydrate in methanol, ethanol, 1-propanol, 2-propanol, and 1-butanol was determined at temperatures ranging from 298.15 to 323.15 K by a solid-liquid equilibrium method. Dissolution thermodynamic studies indicated that the dissolution process of DMHF was endothermic and enthalpy-driven. https://doi.org/10.1016/j.molliq.2017.09.084. Collect powder using special dust vacuum cleaner with particle filter or carefully sweep into suitable waste disposal containers and seal securely. All the models or equations gave satisfactory correlation results. The smell of raspberries is due to lots of molecules, but raspberry ketone is the \"impact molecule\" associated with their particular smell. In addition, thermodynamic analysis indicated an endothermic and spontaneous dissolution behavior of pranlukast hemihydrate in the studied solvents.